您可以添加一个热键，而不是轮询键盘来检查是否按下了某个键。当按下热键q（或您喜欢的任何键）时，将调用触发器函数quit。

import keyboard
import time
import sys

exitProgram = False

# prepare to exit the program
def quit():
    global exitProgram
    exitProgram=True
    
# set hotkey    
keyboard.add_hotkey('q', lambda: quit())

# main loop to do things
while not exitProgram:
    print("Hello")
    time.sleep(1)
    
print("bye bye")
sys.exit()

time.sleep()是阻塞调用。程序运行时不会发生任何事情。
缩短间隔。例如，不是睡10秒，而是睡100 × 0.1秒。

import sys
import time

import keyboard

def hd():
    print("Hi")
    for _ in range(100):
        time.sleep(0.1)
        if keyboard.is_pressed("q"):
            print(keyboard.is_pressed("q"))
            sys.exit()

while True:
    hd()

对于更复杂的行为（在执行实际工作的同时还侦听键盘事件），您将不得不考虑多线程。

如果你把主线程的pid发送给按键回调函数，你可以在子线程中杀死主线程，就像这样：

import os
from time import sleep

import keyboard
import psutil

def on_space():
    print('space was pressed')

def on_x(main_pid):
    print('x was pressed')
    psutilKill(main_pid)

def psutilKill(proc_pid):
    process = psutil.Process(proc_pid)
    for proc in process.children(recursive=True):
        print(f"kill{proc}")
        proc.kill()
    print(f"kill{process}")
    process.kill()

def sleepT(sleepSeconds, msg=""):
    """
    带有倒计时和提示信息的sleep
    """
    while sleepSeconds > 0:
        print(f"\r{msg} sleeping…… %2d 秒" % sleepSeconds, end='')
        sleep(1)
        sleepSeconds = sleepSeconds - 1
    print()

def main():
    main_pid = os.getpid()
    keyboard.add_hotkey('space', on_space)
    keyboard.add_hotkey('x', on_x, args=[main_pid])
    sleepT(100000)

if __name__ == '__main__':
    main()